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| DEL-VECHIO-VIEIRA,GLAUCIEMAR; SANTOS,BRUNA C.S.; ALVES,MARIA SILVANA; ARAÚJO,AÍLSON L.A.; YAMAMOTO,CÉLIA H.; PINTO,MÍRIAM A.O.; KAPLAN,MARIA AUXILIADORA C.; SOUSA,ORLANDO V.. |
| ABSTRACT The present study was designed to investigate the antioxidant, antinociceptive and anti-inflammatory activities of the ethanol extract from Ageratum fastigiatum branches. Phytochemical screening and total phenol and flavonoid contents were determined. The antioxidant activity was assessed by 2,2-diphenyl-1-pycrilhydrazin (DPPH) and iron reducing power methods. The antinociceptive effect was evaluated using the acetic acid-induced writhing, formalin, hot plate and tail immersion assays; while the carrageenan-induced paw edema and pleurisy tests were performed to examine the anti-inflammatory activity against acute inflammation. The extract revealed the presence of flavonoids, tannins, coumarins, terpenes, sterols and saponins. Expressive levels of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ageratum fastigiatum; Analgesic; Anti-inflammatory; Antioxidant; Flavonoids; Total phenols. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401471 |
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| OLIVEIRA,GISELE L.; CARDOSO,SHEILA K.; LARA JÚNIOR,CéLIO R.; VIEIRA,THALLYTA M.; GUIMARãES,ELSIE F.; FIGUEIREDO,LOURDES S.; MARTINS,ERNANE R.; MOREIRA,DAVYSON L.; KAPLAN,MARIA AUXILIADORA C.. |
| ABSTRACTPiper aduncum L. is used in folk medicine to treat respiratory and inflammatory diseases. The aim of this study was to analyze the essential oil from leaves ofP. aduncum collected in the Brazilian Cerrado, North of Minas Gerais, as well as to evaluate the larvicidal activity of this oil and of its major constituent. The essential oil was analyzed by gas chromatography coupled to flame ionization detector and gas chromatography coupled to mass spectrometry that allowed characterizing 23 compounds (monoterpenes: 90.4%; sesquiterpenes: 7.0%). The major component was 1,8-cineole (53.9%). This oil showed to be very different from those obtained from the same species. Larvae of A. aegypti were exposed to different concentrations of the essential oil and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Piper aduncum Aedes aegypti larvicidal activity dengue 1; 8-cineole GC-MS. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401227 |
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| MOREIRA,DAVYSON L.; SOUZA,PATRÍCIA O.; KAPLAN,MARIA AUXILIADORA C.; PEREIRA,NUNO A.; CARDOSO,GERALDO L.; GUIMARÃES,ELSIE F.. |
| The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Piperaceae; Piper solmsianum; Essential oil; Sarisan; Psychopharmacologic effect. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004 |
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| LÓPEZ,KELVIN S.E.; MARQUES,ANDRÉ M.; MOREIRA,DAVYSON DE L.; VELOZO,LEOSVALDO S.; SUDO,ROBERTO T.; ZAPATA-SUDO,GISELE; GUIMARÃES,ELSIE F.; KAPLAN,MARIA AUXILIADORA C.. |
| ABSTRACT Piperaceae species can be found worldwide in tropical and subtropical areas and many of them have been used for centuries in traditional folk medicine and in culinary. In Brazil, species of Piperaceae are commonly used in some communities as local anesthetic and analgesic. Countrified communities have known some species of the genus Ottonia as "anestesia" and it is a common habit of chewing leaves and roots of Ottonia species to relief toothache. The purpose of this study is to report our findings on new molecules entities obtained from the roots of Ottonia anisum Spreng, in which local anesthetic activity (sensory blockage) is demonstrated for the first time in vivo guinea pig model. Phytochemical investigation led to the isolation of three... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Piperaceae; Piper; Ottonia; Amides; Anesthetic properties; Sensory blockage. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000602229 |
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